Papers I browsed

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A few notes of the papers I read.

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Verhoeven, Thibault, et al. “Automated Diagnosis of Temporal Lobe Epilepsy in the Absence of Interictal Spikes.” NeuroImage: Clinical, vol. 17, Elsevier, Jan. 2018, pp. 10–15, doi:10.1016/J.NICL.2017.09.021.

  • Summary:
    • Automatic diagnosis using resting state EEG using directed connectivity and random forest.
  • What is the goal of the paper? What is the problem they are trying to solve?
    • Diagnosis and Laterization of the TLE patients
  • What are the significance?
    • functional connectivity using EEG without scalp pathological activity can be used for automatic diagnosis and lateralization of TLE.
    • 1 min of artefact-free EEG, extracted from a 10- to 15 min recording, which is less time-consuming than other imaging modalities.
  • What are the main technique they are using? How did they solve the problem?
    • Using EEG-based directed functional connectivity
    • Subjects underwent a resting-state eyes-closed recording during presurgical evaluation.
    • Sixty epochs of 1 s, free of artefacts and IEDs, during wakefulness were selected per subject.
    • Random forest
  • What are the important results or knowledge?
    • The hippocampus has a pivotal role in the generation of interictal and ictal activity in the majority of TLE cases.
  • What are the problems in the paper?
    • What about patients for ILAE3-5, and for those that is not laterizated. Quote: especially in difficult cases where the currently used presurgical evaluation methods are not concordant. –> not true
  • How to improve?